Download Citation on ResearchGate | On Dec 31, , Martin H. Floch and others published Dispepsia (dispepsia funcional y dispepsia no ulcerosa) }. Nuestro objetivo fue evaluar los síntomas del síndrome de dispepsia funcional y su mejoría tras la erradicación del Helicobacter pylori. Se evaluaron La dispepsia funcional (DF o dispepsia no ulcerosa) se define como dolor o malestar epigástrico continuo o frecuentemente recurrente para el que no se puede.
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Provavelmente, ulcwrosa droga mais promissora e melhor estudada deste grupo de agentes redutores da sensibilidade visceral seja a fedotozina. New drugs for the treatment of functional dyspepsia. Arq Gastroenterol ;38 3: Current pharmacological treatment of functional dyspepsia is largely empirical and involves anti-secretory or prokinetic drugs.
Aims – To review recent advances in the understanding of the mechanisms involved in symptom production in functional dyspepsia, as well as the development of new drugs that may interfere with these mechanisms, which may lead to more rational and effective treatment of this clinical condition.
Method – Systematic review of papers published in English for the last 10 years. Results – New drugs that increase propulsive gastroduodenal motor activity include new benzamides similar to cisapride, CCK-A blockers, agonists of opiate receptors and motilin agonists similar to erythromycin.
Fucnional number of agents, including sumatriptan and buspirone, stimulates serotonin receptors in the myoenteric plexuses and have been shown to increase gastric accommodation to a meal. Finally, a number of new drugs that ulceroaa increase thresholds for visceral perception or modify sensations is currently under investigation. This includes agents of several groups, such as octreotide, loxiglumide, ondansetron and dlspepsia serotonin blockers, fedotozine and tricyclic antidepressant at low doses.
Conclusions – Although these new drugs may improve the pharmacological approach to the treatment of functional dyspepsia, dispepsai is funcionzl need for randomized, controlled trials to assess their efficacy. Moreover, difficulties related to the identification of the mechanisms underlying symptoms may limit the utilization of these new drugs. Intestinal diseases, drug therapy.
Efficacy of fedotozine in functional dyspepsia: Annu Rev Med ; Clarithromycin accelerates gastric emptying by inducing powerful antral contractions [abstract].
Dispepsia: Causas, Síntomas y Tratamiento –
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New drugs for the treatment of functional dyspepsia
Cisapride or cimetidine in the treatment of functional dyspepsia. Hausken T, Berstad A. Wide gastric antrum in patients with non-ulcer dyspepsia: Effect of glyceryl trinitrate on antral motility and symptoms in patients with functional dyspepsia. Effects of trimebutine maleate on gastric motility in patients with gastric ulcer.
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Dispepsia: Causas, Síntomas y Tratamiento
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Gastrointestinal motor effects of erythromycin.
Motility-modifying agents and management of disorders of gastrointestinal motility. Gastroenterology ; Suppl 1: Amitryptiline improves the quality of life in patients with nonulcer dyspepsia [abstract ]. Efficacy and safety of the peripheral kappa agonist fedotozine funcoinal placebo in the treatment of functional dyspepsia. Dyspepsia, antral motor dysfunction, and gastric stasis of solids. Abnormal clearance of exogenous acid and increased acid sensitivity of the proximal duodenum in dyspeptic patients.
Role of cholecystokinin in the regulation of liquid gastric emptying and gastric motility on humans: Empiric therapy versus diagnostic tests in gastroesophageal reflux disease. A medical decision analysis. Role of impaired gastric accommodation to a meal in functional dyspepsia. A placebo-controlled trial of buspirone, a fundus relaxing drug, in functional dyspepsia: Aliment Pharmacol Ther ;9: Gut ;45 Suppl II: Tanum L, Malt UF. A new pharmacologic treatment of functional gastrointestinal disorder.
A double-blind placebo-controlled study with mianserin.
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Drug treatment of functional dyspepsia. Am J Gastroenterol ; All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Services on Demand Journal. How to cite this article.